Variante Covid brasiliana – Un’infermiera brasiliana si è reinfettata con il virus Sars-Cov-2, con la nuova variante del Sud America, sollevando il timore che questa mutazione ostacoli l’immunità. La variante, che ha spinto il Regno Unito a vietare tutti i voli dal Sud America, è caratterizzata da una mutazione che potrebbe rendere il coronavirus in grado di superare l’immunità sviluppata a seguito di una prima infezione con la versione del virus vecchia.
L’infermiera brasiliana, 45enne, si è ammalata con la nuova variante a ottobre, cinque mesi dopo essersi ripresa da una precedente infezione Covid causata da un ceppo più vecchio. Nella seconda infezione i sintomi della donna sono peggiorati. I ricercatori della Fondazione Oswaldo Cruz, un istituto di scienza di Rio de Janeiro, hanno avvertito che le mutazioni sulla nuova variante potrebbero aumentare il rischio di reinfezione.
“Le evoluzioni virali possono favorire le reinfezioni“, spiegano gli esperti, sottolineando che le varianti individuate di recente “hanno sollevato preoccupazioni sul loro potenziale impatto sull’infettività”. A causa dei crescenti timori sulla variante sudamericana, il governo britannico ha bandito tutti i viaggi provenienti da Portogallo, Sud America, Panama e Capo Verde nel tentativo di proteggere la Gran Bretagna.
Variante Covid brasiliana, ecco cosa sta succedendo
Il segretario ai trasporti Grant Shapps ha affermato di aver ampliato il divieto al solo Brasile per “ridurre il rischio di importare infezioni”. E il principale consigliere scientifico del Regno Unito, Sir Patrick Vallance, ha ammesso ieri sera che “non sappiamo per certo” come la nuova variante influenzerà i vaccini e l’immunità.
Il report della Fondazione Oswaldo Cruz afferma che la donna è stata infettata la prima volta il 26 maggio scorso e all’epoca aveva diarrea, dolori muscolari e debolezza generale. Ha assunto un farmaco per l’asma chiamato prednisone e si è ripresa in circa 3 settimane senza problemi. Successivamente, a ottobre si è ammalata di nuovo con sintomi simili – diarrea, mal di testa, tosse e mal di gola – ed è nuovamente risultata positiva al coronavirus. Rispetto alla prima volta, le sue condizioni sono peggiorate e ha sviluppato difficoltà respiratorie, mancanza di respiro, dolori muscolari e insonnia.
Quando i ricercatori hanno confrontato i campioni dei test positivi effettuati a maggio e a ottobre, hanno scoperto che l’ultimo presentava mutazioni ora note per essere una componente chiave della variante brasiliana. La mutazione genetica, chiamata E484K, cambia la forma della proteina spike all’esterno del virus in un modo che potrebbe renderla meno riconoscibile a un sistema immunitario “addestrato” a individuare versioni del virus che non hanno la mutazione.
Si pensa che E484K modifichi il virus in un modo che renda più difficile per gli anticorpi legarsi ad esso per impedirgli di entrare nel corpo. Gli anticorpi sono una parte del sistema immunitario che può paralizzare i virus o attaccarsi ad essi e segnalarli come bersagli per altri globuli bianchi “killer”.
In questo caso, la parte della proteina spike che viene modificata è chiamata “dominio di legame del recettore”, o RBD, che il virus utilizza per attaccarsi al corpo.
I ricercatori di Oswaldo Cruz hanno scritto: “L’analisi delle mutazioni ha dimostrato, per la prima volta, un caso di reinfezione con una variante virale che ospita la mutazione E484K, situata in un residuo chiave del dominio di legame del recettore, che sembra aumentare modestamente il legame tra la proteina Spike e il corpo”.
Gli scienziati hanno detto che il caso dell’infermiera è il primo di reinfezione con la variante. E suggeriscono che le differenze causate dalla mutazione alla proteina spike significano che l’immunità naturale sviluppata dal suo corpo dopo la prima infezione non è stata in grado di proteggerla dalla seconda.
La variante brasiliana è già nel Regno Unito. Lo ha confermato uno degli esperti di punta del Paese, la professoressa Wendy Barclay, dell’Imperial College di Londra, secondo la quale inoltre la mutazione rilevata in Brasile ha “due varianti” e solo di una per ora è stata accertata la circolazione in Gran Bretagna. Lo riporta il Daily Mail.
fonte: agi.it
[…] la preoccupazione per la cosiddetta variante brasiliana di coronavirus Sars-CoV-2. Ne ha parlato anche Massimo Galli, infettivologo dell’ospedale Sacco e […]
Nach Überprüfen aus einer Kartendeck von Bericht Karten, es wahrscheinlich bis geworden klug, Versuch ihre Kunststoff Alternativen.
Nonetheless, in online poker, the possibility of getting lots of
palms is superior because of the speed and multi tasking features.
Does your blog have a contact page? I’m having a tough time locating it but, I’d like to send you an e-mail. I’ve got some creative ideas for your blog you might be interested in hearing. Either way, great website and I look forward to seeing it develop over time.
Hiya, I’m really glad I have found this info. Nowadays bloggers publish just about gossips and internet and this is actually annoying. A good site with interesting content, that is what I need. Thank you for keeping this web site, I’ll be visiting it. Do you do newsletters? Cant find it.
Hello. fantastic job. I did not anticipate this. This is a fantastic story. Thanks!
There are some attention-grabbing cut-off dates on this article but I don’t know if I see all of them center to heart. There is some validity but I will take hold opinion till I look into it further. Good article , thanks and we want extra! Added to FeedBurner as effectively
Wow! Thank you! I continuously wanted to write on my site something like that. Can I implement a part of your post to my website?
Very interesting details you have remarked, thankyou for posting.
As I site possessor I believe the content material here is rattling wonderful , appreciate it for your efforts. You should keep it up forever! Best of luck.
Hi, Neat post. There’s a problem with your website in internet explorer, would check this… IE still is the market leader and a large portion of people will miss your wonderful writing because of this problem.
F*ckin¦ tremendous things here. I am very happy to peer your article. Thank you a lot and i am looking ahead to touch you. Will you please drop me a mail?
You can certainly see your expertise in the paintings you write. The arena hopes for even more passionate writers like you who aren’t afraid to say how they believe. All the time go after your heart. “Every man serves a useful purpose A miser, for example, makes a wonderful ancestor.” by Laurence J. Peter.
Thanks a bunch for sharing this with all of us you actually know what you’re talking about! Bookmarked. Please also visit my web site =). We could have a link exchange agreement between us!
Thanks for sharing excellent informations. Your site is so cool. I am impressed by the details that you¦ve on this blog. It reveals how nicely you understand this subject. Bookmarked this website page, will come back for extra articles. You, my pal, ROCK! I found simply the information I already searched everywhere and just could not come across. What a great website.
There are some fascinating time limits on this article but I don’t know if I see all of them heart to heart. There is some validity however I will take maintain opinion until I look into it further. Good article , thanks and we would like more! Added to FeedBurner as effectively
Hello very cool website!! Guy .. Excellent .. Wonderful .. I’ll bookmark your website and take the feeds additionally?KI am satisfied to find so many helpful information here within the publish, we’d like work out extra strategies on this regard, thank you for sharing. . . . . .
Hello. remarkable job. I did not anticipate this. This is a fantastic story. Thanks!
Hello my friend! I want to say that this post is amazing, nice written and come with almost all significant infos. I?¦d like to see more posts like this .
I’m impressed, I have to say. Really hardly ever do I encounter a blog that’s both educative and entertaining, and let me let you know, you have hit the nail on the head. Your idea is outstanding; the issue is something that not enough persons are speaking intelligently about. I am very glad that I stumbled throughout this in my seek for something relating to this.
Dolgulu Diş Neden Ağrır? Dolgulu Diş Ağrısı Sebepleri
Dolgulu diş ağrısı, genellikle dolgunun hasar görmesi, çatlaması veya çürümesi nedeniyle ortaya çıkabilir. Dolgu, dişin çürük veya hasarlı bölgesini onarmak için kullanılır, ancak zamanla bu dolgu malzemesi aşınabilir veya zarar görebilir. Eğer dolgu kötü bir şekilde yerleştirilmişse, kenarlarında çatlaklar oluşabilir ve bu durum ağrıya neden olabilir. Ayrıca, dolgulu dişin çevresindeki diş dokusunda çürüme başlarsa, ağrı hissedilebilir. Diş eti çekilmesi de dolgulu dişlerde hassasiyete ve ağrıya yol açabilir. Ağrılı dolgu durumunda, diş hekimine başvurmak önemlidir. Diş hekimi, ağrının nedenini belirleyerek uygun tedaviyi önerir, dolgu yeniden yapılabilir veya diğer tedavi seçenekleri değerlendirilebilir.
Diş eti kanaması, genellikle diş etlerindeki hassasiyet, şişme ve kızarıklık ile karakterize edilen bir durumdur. Bu durum, genellikle diş eti iltihabının bir belirtisi olarak ortaya çıkar.
Diş eti iltihabı, plak birikiminin diş etleri etrafında birikmesi ve bakterilerin çoğalması sonucunda meydana gelir. Diş eti iltihabı, diş etlerini zayıflatarak, kanamaya ve diş etlerinin çekilmesine neden olabilir. Diş eti kanamasının nedenleri arasında düzensiz diş fırçalama, diş ipi kullanmama, kötü ağız hijyeni, hormonal değişiklikler, vitamin eksiklikleri ve bazı sistemik hastalıklar bulunabilir. Ayrıca, sigara içme alışkanlığı da diş eti kanamasını artırabilir.
SEO Nedir? Nasıl Yapılır?
SEO (Search Engine Optimization), arama motorları tarafından web sitelerini daha iyi anlamalarını ve değerlendirmelerini sağlamak amacıyla yapılan bir dizi teknik ve stratejik uygulamayı içeren bir dijital pazarlama disiplinidir. Temel olarak, bir web sitesinin arama motoru sonuç sayfalarındaki sıralamasını artırmayı hedefler.
SEO’nun ana unsurları arasında anahtar kelime optimizasyonu, içerik kalitesi, teknik altyapı iyileştirmeleri, backlink oluşturma ve kullanıcı deneyimi bulunur. Anahtar kelimelerle uyumlu, kaliteli içerikler üretmek, web sitesinin arama motorları tarafından daha iyi anlaşılmasını sağlar. Teknik olarak düzgün bir yapı, arama motorlarının içeriği indekslemesini kolaylaştırırken, backlinkler ve kullanıcı deneyimi de sıralamalara etki eden diğer önemli faktörlerdir.
SEO, sürekli takip ve güncellemeler gerektiren dinamik bir süreçtir. İyi bir SEO stratejisi, web sitesinin organik trafik ve görünürlüğünü artırarak online başarıyı destekler.
so much good information on here, : D.
I’d have to examine with you here. Which is not one thing I usually do! I take pleasure in reading a post that may make folks think. Additionally, thanks for permitting me to comment!
I don’t even know how I ended up here, but I thought this post was good. I don’t know who you are but definitely you are going to a famous blogger if you are not already 😉 Cheers!
FitSpresso is a natural weight loss supplement that will help you maintain healthy body weight without having to deprive your body of your favorite food or take up exhausting workout routines.
Fantastic site. Lots of useful information here. I am sending it to some buddies ans additionally sharing in delicious. And certainly, thanks on your effort!
I have recently started a site, the information you offer on this web site has helped me greatly. Thanks for all of your time & work.
I was suggested this web site by my cousin. I’m not sure whether this post is written by him as no one else know such detailed about my problem. You are amazing! Thanks!
I?¦ve learn a few good stuff here. Certainly value bookmarking for revisiting. I surprise how a lot effort you set to create such a fantastic informative web site.
Hello. splendid job. I did not expect this. This is a excellent story. Thanks!
I¦ve recently started a web site, the info you offer on this site has helped me greatly. Thanks for all of your time & work.
I’d always want to be update on new posts on this web site, saved to bookmarks! .
FitSpresso is a weight loss supplement designed for individuals dealing with stubborn body fat.
Hey very nice website!! Man .. Beautiful .. Wonderful .. I’ll bookmark your site and take the feeds alsoKI am satisfied to search out a lot of helpful info right here within the publish, we want work out more techniques on this regard, thanks for sharing. . . . . .
I have been absent for some time, but now I remember why I used to love this web site. Thank you, I’ll try and check back more frequently. How frequently you update your site?
Real wonderful visual appeal on this website , I’d rate it 10 10.
I used to be very happy to search out this web-site.I wanted to thanks for your time for this glorious learn!! I positively enjoying every little little bit of it and I have you bookmarked to take a look at new stuff you blog post.
My brother suggested I might like this website. He was totally right. This post actually made my day. You cann’t imagine just how much time I had spent for this information! Thanks!
Heya i am for the first time here. I found this board and I find It really useful & it helped me out much. I hope to give something back and aid others like you aided me.
I was curious if you ever thought of changing the structure of your blog? Its very well written; I love what youve got to say. But maybe you could a little more in the way of content so people could connect with it better. Youve got an awful lot of text for only having one or two images. Maybe you could space it out better?
My spouse and I stumbled over here from a different web address and thought I may as well check things out. I like what I see so now i’m following you. Look forward to checking out your web page yet again.
Thankyou for helping out, superb information.
I was reading through some of your blog posts on this website and I think this site is very informative ! Retain putting up.
Lottery Defeater: What Is It? A software tool called Lottery Defeater was created to raise the odds of winning lottery tickets.
you have a great blog here! would you like to make some invite posts on my blog?
Great ?V I should definitely pronounce, impressed with your website. I had no trouble navigating through all tabs and related info ended up being truly easy to do to access. I recently found what I hoped for before you know it at all. Quite unusual. Is likely to appreciate it for those who add forums or something, website theme . a tones way for your client to communicate. Excellent task..
I will immediately grab your rss feed as I can not in finding your e-mail subscription hyperlink or newsletter service. Do you have any? Kindly allow me recognize in order that I may subscribe. Thanks.
When I originally commented I clicked the -Notify me when new comments are added- checkbox and now each time a remark is added I get four emails with the same comment. Is there any manner you’ll be able to remove me from that service? Thanks!
I have not checked in here for a while since I thought it was getting boring, but the last several posts are great quality so I guess I will add you back to my everyday bloglist. You deserve it my friend 🙂
Your style is so unique compared to many other people. Thank you for publishing when you have the opportunity,Guess I will just make this bookmarked.2
I was studying some of your content on this site and I believe this website is really informative! Keep on putting up.
Magnificent goods from you, man. I’ve understand your stuff previous to and you’re just extremely great. I really like what you’ve acquired here, certainly like what you’re saying and the way in which you say it. You make it enjoyable and you still take care of to keep it smart. I cant wait to read far more from you. This is actually a tremendous website.
Almost all of the things you say happens to be astonishingly legitimate and that makes me ponder why I hadn’t looked at this with this light previously. This article truly did switch the light on for me personally as far as this specific topic goes. Nonetheless there is actually one position I am not too comfy with so whilst I attempt to reconcile that with the actual central theme of your point, let me observe what the rest of your readers have to point out.Well done.
Thanks for sharing excellent informations. Your site is so cool. I am impressed by the details that you’ve on this site. It reveals how nicely you understand this subject. Bookmarked this web page, will come back for more articles. You, my pal, ROCK! I found just the information I already searched everywhere and simply could not come across. What a perfect website.
I have been reading out some of your stories and it’s pretty clever stuff. I will make sure to bookmark your website.
I like this blog so much, saved to favorites. “Respect for the fragility and importance of an individual life is still the mark of an educated man.” by Norman Cousins.
What i do not realize is if truth be told how you are not really much more neatly-liked than you might be now. You’re very intelligent. You know therefore considerably with regards to this matter, made me for my part consider it from so many various angles. Its like men and women are not involved except it is one thing to accomplish with Girl gaga! Your personal stuffs great. All the time care for it up!
FitSpresso: What Is It? FitSpresso is a natural weight loss aid designed for individuals dealing with stubborn weight gain. It is made using only science-backed natural ingredients.
What is Lottery Defeater Software? Lottery Defeater Software is a plug-and-play Lottery Winning Software that is fully automated. Kenneth created the Lottery Defeater software. Every time someone plays the lottery, it increases their odds of winning by around 98.
hello there and thank you for your info – I have definitely picked up anything new from right here. I did however expertise some technical issues using this website, as I experienced to reload the website many times previous to I could get it to load correctly. I had been wondering if your hosting is OK? Not that I’m complaining, but sluggish loading instances times will sometimes affect your placement in google and can damage your high quality score if advertising and marketing with Adwords. Well I am adding this RSS to my email and could look out for a lot more of your respective interesting content. Ensure that you update this again soon..
This design is wicked! You certainly know how to keep a reader entertained. Between your wit and your videos, I was almost moved to start my own blog (well, almost…HaHa!) Wonderful job. I really loved what you had to say, and more than that, how you presented it. Too cool!
Very nice info and right to the point. I don’t know if this is really the best place to ask but do you guys have any thoughts on where to get some professional writers? Thanks 🙂
It’s a shame you don’t have a donate button! I’d most certainly donate to this excellent blog! I suppose for now i’ll settle for bookmarking and adding your RSS feed to my Google account. I look forward to brand new updates and will talk about this website with my Facebook group. Talk soon!
My brother recommended I might like this web site. He was totally right. This post actually made my day. You can not imagine simply how much time I had spent for this information! Thanks!
Very interesting info !Perfect just what I was searching for! “Wherever the Turkish hoof trods, no grass grows.” by Victor Hugo.
This site is truly addictive! Always filled with current and interesting content.
I learn something new every visit. The content is carefully and professionally prepared.
I learn something new every visit. The content is carefully and professionally prepared.
This site is truly amazing! The content is high quality, and I always find what I’m looking for. Thank you!
A fantastic resource! The content is both informative and entertaining. I definitely recommend it.